Evidence of circadian effects on phytochemical content and antioxidant potential of Ficus bubu extracts
DOI:
https://doi.org/10.13171/mjc02505191805mbossoAbstract
Ficus bubu Warb. is a member of the Moraceae family, which includes species of the same genus with numerous therapeutic virtues. No other studies besides antimicrobial and antiproliferative activities have been conducted on Ficus bubu. Current research aims to observe the influence of circadian rhythms on the qualitative and quantitative phytochemical analysis and to evaluate the antioxidant activity of ethanolic extracts from leaves, stem bark, and roots, taken at different times of day (6 am, 12 pm, 6 pm), making 09 samples processed separately. Secondary metabolites were identified qualitatively using insoluble complex formation or color reactions, and quantitatively using a spectrophotometer at specific wavelengths. Antioxidant activity was assessed by DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging, iron reduction (FRAP), and phosphomolybdenum methods. The results show that leaves (10L1Fb) harvested in the morning show the most promising activity, followed by stem bark (10B3Fb) in the evening and roots (10R2Fb) at midday. These extracts demonstrate significant antioxidant potential, suggesting that Ficus bubu could be a promising natural source for developing new drugs, notably in treating rheumatoid arthritis, cancer, cardiovascular disease, malaria, etc.
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