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Chemical Composition, Antioxidant and Anti-acetylcholinesterase activities of Tunisian Crithmum maritimum L. Essential oils

Asma Nguir, Malek Besbes, Hichem Ben Jannet, Guido Flamini, Fethia Harzallah-Skhiri, M’hamed Ali Hamza


 acetylcholinesterase properties of the aerial parts and roots essential oils from Crithmum maritimum L., Apiaceae, gathered in the area of Monastir (Tunisia). The essential oils have been analysed by GC and GC-MS. Remarkable differences were found between the constituent percentages of the different studied organs. The most important compounds from the aerial parts were: γ-terpinene (39.3%), methylcarvacrol (21.6%) and p-cymene (11.8%). In the roots oil, the main components were terpinolene (36.9%), dillapiole (26.8%) and γ-terpinene (21.9%). The antioxidant activity of the two oils was evaluated by employing 2,2-diphenyl-1-picrylhydrazyl hydrate (DPPH) and 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging tests. The results showed that the antioxidant capacity assessed by different in vitro tests were moderate, the ABTS assay after 20 min (IC50 = 0.051 mg/mL) of aerial parts and (IC50 = 0.643 mg/mL) of the roots, appeared to be more potent than that for the DPPH assay (IC50 = 0.92 mg/mL) of aerial parts and (IC50 = 0.048 mg/mL) of roots. In addition, the examined oils showed the highest AchE inhibitory 1 mg/mL activity (31.16% and 26.35%, for the aerial parts and roots, respectively).

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