New biologically active allelochemical from the leaves of Dalbergia Paniculata Roxb
DOI:
https://doi.org/10.13171/mjc02301311676singhAbstract
A new biologically active Allelochemical 3,5,7,3’,4’-pentahydroxyflavone-3-O-β-D xylopyranosyl -(1→4)- β-D-glucopyranosyl-4’-O-α-L-arabinoside (A1) whose m.p. is 340–345 0C, m.f. [M+] 728 (EIMS) was isolated from methanolic leaf extracts of Dalbergia paniculata Roxb. It was characterized by several color reactions, spectral analysis FTIR, 1H-NMR, GC-MS, and chemical degradations. The results of the antimicrobial activity of (A1) at high concentration (100µg/mL) was 20, 17, and 15 mm zone of inhibition against E. coli, B. cereus, and S. aureus aeruginosa, respectively. The data demonstrated that the antimicrobial activity of CH3 OH soluble fraction (A1 ) at all concentrations was highest against E. coli and lowest S. aureus. E. coli, B. cereus, and S. aureus aeruginosa, respectively 7.3, 2.1, and 0.02mm, MIC was defined as the minimum concentration of assayed samples that inhibited the visible growth of the tested microorganism. MIC in E. coli, B. cereus, and S. aureus aeruginosa was 7.3, 2.1, and 0.02mm, respectively.References
- D. M. Verma, N. P. Balakrishnan, R. D. Dixit, flora of Madhya Pradesh: Pteridophytes and Angiosperms (Ranunculaceae to Plumbaginaceae), Botanical Survey of India, 1993, 1.
- R. N. Chopra, S. L. Nayar, I. C. Chopra, L. V. Asholakar, K. K. Kakkar, O. J. Chakra, B. S. Varma, Glossary of Indian medicinal plants with active principles, New Delhi, 1992, 1, 187.
- S. N. Chaitra, N. K. Chaitra, P. Shalini, R. Sindhu, K. M. Saru Raj, Phytochemical Analysis and antibacterial activity of Dalbergia paniculata Roxb., International Journal of pharmaceutical science and research, 2015, 6, 712-716.
- P. M. Dewick, Isoflavonoids, In the flavonoids advance in research since1986, Harbone J. B., Chapman and Hall, NY, 1994, 117-238.
- D. M. X. Donnelly, G. Boland Neoflavonoids, Harbone J. B., (Ed) Chapman and Hall., In the flavonoids advance in research science, NY, 1994, 239-258.
- I. Shaik. Khalivulla, A. K. B. Reddy, D. Gunasekar, M. M. Murthy, Tadikimalli p, Alain Blond and Bernard bodo, A new C-geranylated Isoflavone from Dalbergia paniculata Roxb., 2007, 11, 1109-1111.
- V. Narayanan, T. R. Seshadri, Paniculatin, A new isoflavone-di-C- glucoside of Dalbergia paniculata Roxb. bark. Indian Journal of Chemistry, 1997, 9, 14-16.
- D. Adinaravana D, J. R. Rao, Isoflavonoid glycosides of Dalbergia paniculata Roxb., The constitution of Dalpenitin and Dalpatin, Tetrahedron, 1972, 28, 5377-5384.
- M. R. Parthasarathy, T. R. Seshadri, R. S. Verma, Minor isoflavonoid glycosides of stem bark of Dalbergia paniculata Roxb. isolation of a new
C-glycoside, current science, 1974, 43, 74-75.
- M. R. Parthasarathy, T. R. Seshadri, R. S. Verma,7-O-Rutinosides of biochanin A and formononetin, Two new rhamnoglucosides from the bark of Dalbergia paniculata Roxb., India journal of chemistry, 1974, 12, 518-519.
- D. Adinarayana, J. R. Rao, Dalpanin, A C-glycosylisoflavanone from Dalbergia paniculata Roxb. Proceedings of Indian academy of science, 1975, 81A, 23-31.
- D. Adinarayana, J. R. Rao, Isoflavonoids of Dalbergia paniculata, Indian Journal of Chemistry, 1975, 13, 425-426.
- M. R. Parthasarathy, T. R. Seshadri, R. S. Verma, New Isoflavonoidglycosides from Dalbergia paniculata Roxb., Phytochemistry, 1976, 15, 1025-1027.
- M. Radhakrishniah, Chemical constituents of Dalbergia paniculata Roxb. root, Journal of Indian chemical society, 1979, 56, 81-86.
- M. R. Parthasarathy, P. Sharma, S. B. Kalidhar, Isocavuinin-7-Oglucoside, from bark of Dalbergia paniculata Roxb., Indian Journal of Chemistry, 1980, 19B, 429-430.
- J. R. Rao, R. S. Rao, Dalpalatin, A new isoflavone from Dalbergia paniculata Roxb seeds Indian Journal of Chemistry, 1990, 29B, 78-79.
- J. R. Rao, R. S. Rao, Dalpaniculin, A C-glycosyl isoflavone from Dalbergia paniculata Roxb. seeds, Phytochemistry, 1991, 30, 715-716.
- N. P. Leena, N. A. Aleykutty, Isolation and spectral identification of quercetin from the alcoholic root extract of Clerodendrum paniculatum Linn., International Journal of pharma science and research, 2016, 7, 47-50.
- G. Venugopal, C. S. Reddy, B. N. Rao, V. B. Rao, T.V. Rao, A. P. Rao, pharmacognostic and preliminary phytochemical evaluation of Ocimum basilicum L.var.pilosum(Willd.) benth. and Otenuiflorum var. CIM-AYU, International Journal of Pharmacognosy and Phytochemical Research, 2015, 7, 519-526.
- E. J. Park, Y. Kim, Journal of Natural Products, 63, 2000, 34-36.
- S. Chaitra, N. N. Kumar, P. Shalini, R. Sindhu, K. M. S. Raj, Phytochemical Analysis and Antimicrobial activity of Dalbergia paniculata
Roxb., International Journal of pharmaceutical science and research, 2015, 6, 712-716.
- E. Leder, M. Lederer, Chromatography, Elsevier publishing company, New York, 1247, 1957.
- L. V. Nho, P. D. Thang, V. V. Sy, N. H. Hoang, P. T. Huong, Antimicrobial activity and chemical investigation of Pongamia pinnata L. Leaf Journal of Pharmacognosy and phytochemistry, 2022, 11(4), 30-32.
- F. S. Mohammed, E. Kına, İ. Uysal, K.Mencik, M. Dogan, M. Pehlivan, M. Sevindik, Antioxidant and Antimicrobial Activities of Ethanol Extract of Lepidium spinosum Turkish Journal of Agriculture - Food Science and Technology, 2022, 10(6), 1116-1119.
- R. Gurung, S. Adhikari, K. Parajuli, Evaluation of the Antibacterial and antioxidant activity of Mimosa rubicaulis and Reinwardtia indica Evidence-Based, Complementary and Alternative Medicine, 2020, 6, 3862642.
-D. Sunil, S. Shinde, S. Kanshette, D. M. Jadhav, HPTLC profiling and antibacterial studies of Cassia tora L. against some pus-forming bacteria, International Journal of Botany Studies, 2022, 7, 527-532.
-K. Ananda Lakshmi, Review on biosynthesis of silver nanoparticles and its characterization plant archives, 2021, 21, 2393-2400.
- S. B. Mishra, V. K. M. Rao, S. K. Bose, Quantitative estimation of carbohydrates by paper partition chromatography, Journal of Scientific and Industrial Research, 1960, 173-176.
- E.L. Hirst, L. Hough, J. K. N. Jones, Composition of the gum of Sterculia setigera: occurrence of D-tagatose in nature, Journal of chemical society, 1949, 177-177.
-J.Shinoda, J Pharm Soc Japan, 1928, 48, 214.
-K.S. Szablewska, T. Szablewski , A. P. Balcerek , L. Szwajkowska, M. M. .Krzyzaniak, D. .Swierk, R. C..Radziejewska and Z. Krejpcio, Antimicrobial Activities Evaluation and Phytochemical Screening of Some Selected Plant Materials Used in Traditional Medicine, MDPI, 2023, 28, 244.
-S. Abubakar, O.A. Adoum, Antimicrobial Activity and Brine Shrimp Lethality Test of cassia Sieberiana D.C. Leaves Extracts, Chemistry Research Journal, 2021, 6(6), 148-15.
Downloads
Published
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).