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1,3-Dipolar cycloaddition of azomethine ylide from Phtaloylimidophenylalanyl-2-hydroxymethylaziridine

Assia Keniche, Wassila Drici, Mohamed Zakaria Slimani, Abdelmoumen Mezrai, Joseph Kajima Mulengi

Abstract


Phtaloylimidophenylalanyl-2-hydroxymethylaziridine has been used as a starting material to yield azomethine ylide through thermal opening and was then involved into 1,3-dipolar cycloaddition reactions. Different five-membered adducts were obtained and were fully identified. The latter might be considered useful starting materials for further functionalization to provide novel compounds of biological interest.


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DOI: http://dx.doi.org/10.13171/mjc.2.4.2013.07.09.12

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